Toxic Ingestion/Acute Tricyclic Antidepressant (TCA) Ingestion
نویسندگان
چکیده
منابع مشابه
Benzodiazepines co-ingestion in reducing tricyclic antidepressant toxicity.
AIM Tricyclic antidepressant (TCA) overdose is generally associated with central nervous system (CNS) and cardiovascular toxicity manifested by seizure, electrocardiographic (ECG) abnormalities and arrhythmia. The objective of this study was to determine whether TCA toxicity would be reduced in patient where benzodiazepine (BDZ) was co-ingested with TCA. DESIGN Patients who were diagnosed to ...
متن کاملEpidemiology of fatal tricyclic antidepressant ingestion: implications for management.
Although there is a large body of literature documenting the lethal cardiotoxic complications of tricyclic antidepressant (TCA) overdose, the absence of reliable predictive signs has led to a policy of admitting even trivial-appearing overdoses for inpatient observation. A study of 18 fatal cases revealed that with the exception of two that received clearly inadequate medical care, all fatal in...
متن کاملTricyclic antidepressant toxicity.
Tricyclic antidepressants are dibenzazepine derivatives with adrenergic, anticholinergic, and direct cardio-depressant activity. Double-blind clinical studies show TCAD to be efficacious for two-thirds of depressed patients. Cardiac toxicity is significant, especially on diseased myocardium. Serious arrhythmias and intracardiac blocks have been reported on therapeutic doses. Tricyclic antidepre...
متن کاملTricyclic antidepressant overdose: a review.
Overdoses of tricyclic antidepressants are among the commonest causes of drug poisoning seen in accident and emergency departments. This review discusses the pharmacokinetics, clinical presentation and treatment of tricyclic overdose.
متن کاملSignificant toxicity in a young female after low-dose tricyclic antidepressant ingestion.
BACKGROUND Tricyclic antidepressant (TCA) ingestions are a relatively common pediatric ingestion, with significant potential for both cardiac and neurological toxicity. Previous studies on pediatric TCA ingestions have found the threshold of toxicity to be 5 mg/kg. CASE We report a case of an 8-year-old girl who presented to the emergency department with depressed mental status and seizure-li...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: MedEdPORTAL
سال: 2015
ISSN: 2374-8265
DOI: 10.15766/mep_2374-8265.10227